【前沿】Handling of Thyroid Follicular Patterned Lesions

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Handling of Thyroid Follicular Patterned Lesions
Juan Rosai
Endocrine Pathology 2005, 16(4):279-283.

For lesions having obvious PTC-type nuclear changes:
• Papillary thyroid carcinoma, follicular variant, regardless of the status of the capsule.

For lesions having questionable PTC-type nuclear changes, for tumor showing definite capsular invasion:
• Follicular carcinoma.
For tumor showing questionable capsular invasion:
• Follicular tumor of uncertain malignant potential (FT-UMP), if PTC-type nuclear changes are absent.
• Well-differentiated tumor of uncertain malignant potential (WDT-UMP), if those nuclear changes are questionable.

Follicular carcinoma
　Encapsulated
　　With capsular invasion only
　　With limited (<4) vascular invasion
　　With extensive (≥4) vascular invasion
　Widely invasive

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