关于镍铬烤瓷浙江省已上报国家药监局，顺便大家也讨论一下

w****0

这话题目前来说比较关注，如果真有这么一会事。以后也就只能做贵金属烤瓷和全瓷。

w****0

这样贵金属烤瓷和全瓷不是一般的绝大部分的人能接受:(

s****0

非贵金属烤瓷冠修复后牙龈组织和血液中镍铬元素含量分析

i***牙

最近几天关于镍铬合金导致肾病的报道再度引发了广大患者和同行们对于这种合金生物安全性的质疑，园子里也有很多战友对此议论纷纷，我个人认为对于这种专业性很强的问题，必须找到相应的文献、理论支持，才能理清头绪、拨乱反正，至少我们作为口腔医生的代表，应该对全体患者有一个公允而且统一的解释或者交待，才能有效地抵消这一事件对于整个口腔医疗环境的干扰，任何武断或者模棱两可的言论，只能加重整个患者群体对医疗服务的戒备，最终打击全体口腔医生。

在这里，响应xqg1981斑竹的号召，摘录一篇这方面的文献回顾，希望大家展开进一步的讨论：

The safety of nickel containing dental alloys

Dental materials , Volume 22, Issue 12, Pages 1163-1168 (December 2006)

Abstract
Nickel is a constituent of many dental alloys. This paper reviews mainly papers published after 1985 with regards to biological reactions to nickel in dentistry. Nickel is an allergen, but there is no evidence that individual patients are at a significant risk of developing sensitivity solely due to contact with nickel-containing dental appliances and restorations. Hypersensitivity reactions to nickel are only likely to occur with prior sensitization from non-dental contacts and even these are rare. Clinical evidence has been presented to show that small doses of nickel, e.g. from dental appliances, may induce tolerance to this allergen. The papers reviewed report low rates of release of nickel from dental alloys. Some nickel compounds, which are mildly cytotoxic, have been implicated as carcinogens by inhalation in industrial settings, but these compounds are not present in dentistry-related operations, including dental technology procedures. Nickel-containing alloys and compounds have not been associated with increased cancer risk by oral or dermal routes of exposure. It is concluded that, subject to use according to established techniques, nickel-containing dental alloys do not pose a risk to patients or members of the dental team.

含镍牙科合金的安全性

牙科材料学杂志，第22卷，第12期，第1163-1168页，2006年12月

镍是一种很多牙科合金中都含有的成分的，本论文回顾了自1985年以来发表的关于镍生物安全性的文献。镍属于一种致敏原，但是没有证据表明患者可以仅仅由于接触含镍的器械或者修复体而发生明显的过敏反应。镍的接触过敏反应，往往倾向发生于以前因非口腔途径接触镍而致敏的病例，而这种情况是很少见的。临床证据表明，像牙科修复体那样小剂量的镍接触，可能引导肌体对这种致敏原产生耐受。本论文回顾的文献反映了确实有少量的镍元素可以从牙科合金中游离出来，部分镍的复合物具有轻度的毒性，而且有致突变倾向，但是这些复合物仅仅出现在工业领域，而不出现在牙科操作或者牙科技工中。当前，镍以及其复合物还没有被认定为口腔癌和皮肤癌的接触致病因素，只要遵照既有的技术程序，含镍合金并不会对医生或者患者产生健康危害。

a****x

我认为应该由国家来下个定论,但是我们应该坚决维护,口腔的医疗环境,

流**点

钛合金烤瓷是否含镍-铬？

x****5

没问题的   那都是在正常范围之内的

d****n

钴铬合金的不是没有镍吗？干嘛非得做高金和全瓷啊

f****9

钛合金的也含有少量的镍-铬