求翻译

z****y

An atypical form of macrocytosis termed volumetric macrocytosis is described. In contrast to the macrocyte associated with megaloblastic anemia and the pseudomacrocyte caused by viscoelastic defects, the volumetric macrocyte is characterized by an increased mean corpuscular volume and a normal cell diameter. The volumetric macrocyte proves to be thicker than the normocytic red blood cell. This large erythrocyte is overhydrated and contains an increased quantity of hemoglobin. The cell has many characteristics in common with the red blood cells of neonates. Volumetric macrocytosis accompanies sustained hydroxyurea therapy and may represent a drug-induced dyserythropoiesis.

l****8

非典型形式的大红细胞症称为体积大红细胞症的描述。与此相反的巨红细胞与巨幼细胞性贫血和pseudomacrocyte造成粘缺陷，体积巨红细胞的特点是增加平均红细胞体积和正常细胞直径。体积巨红细胞被证明是厚比正常红细胞红血细胞。这个大的红细胞是overhydrated和包含一个数量增加血红蛋白。细胞有许多共同特点的红血细胞的新生儿。体积大红细胞症伴随持续羟基脲治疗和可能是药物引起的红细胞生成障碍。

求*医

体积大红细胞症被描述为非典型式的大红细胞症。与巨红细胞与巨红细胞性贫血和伪巨红血球引起的粘弹性缺陷形成对照，体积大红细胞症可以通过血球比容和正常细胞直径平均值增加来诊断的。患者血液中的大红细胞被证明为体积大（厚）于正常红血球。此类大红细胞是成水合物，且包含过量血红蛋白，且与新生儿红细胞有许多共同特征。体积大红细胞症伴随持续的羟基脲治疗产生，可能是药物引起的红细胞生成障碍。