The Relativities Between the Immunological Indexes and The therapeutical result of the Bone Metastases Patients Treated With 89SrCl2
[Abstract] Objective To investigate the influence of 89SrCl2(strontium-89 chloride) on the immunological functions in the patients with bone metastases , and study the relativities between the immunological indexes and prognosis of the patients . Methods 25 patients who were diagnosed by clinic were treated with 89SrCl2 . The CD4+、CD8+、CD4+/CD8+、were detected before and after 89SrCl2 treatment , as well in 20 controls . The difference of immunological indexes between the survivals and deaths were also compared . Result The indexes between the patients and controls 、before and after the therapy were different significantly(p<0.05) . The indexes of the deaths were differ to that of the survivals (p<0.05) . Conclusion The immunological functions in the patients with bone metastases were inhibited obviously . Treating with 89SrCl2 can improve their functions to a certain extent . The recover level of the inefficacious patients was lower than that of the efficacious patients. .
[Keywords] Bone metastases ; immunological functions ; T lymphocyte subsets ; 89SrCl2
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